We have a stretegic alliance with Shire AG to develop ZFP Therapeutics for hemophilia, Huntington's disease and other monogenic diseases.
In addition, we have out-licensed non-therapeutic applications of our ZFP technology in high value laboratory research reagents, transgenic animals and commercial production cell lines to Sigma-Aldrich Corporation, and in plant agriculture to Dow AgroSciences LLC, a subsidiary of Dow Chemical Corporation.
- Sigma is developing and marketing ZFN-derived gene editing tools under the trademark CompoZr®, ZFP-modified cell lines for commercial production of protein pharmaceuticals through its SAFC® business unit, and ZFP-engineered transgenic animals through its SAGE™ Labs business unit.
- Dow AgroSciences has the exclusive right to use Sangamo’s ZFP technology in plants and is marketing ZFP-derived plant products under the trademark EXZACT™ Precision Technology. We have retained rights to use plants or plant-derived products to deliver ZFP TFs or ZFNs into human or animals for diagnostic, therapeutic, or prophylactic purposes.
- In addition, Genentech which has a non-exclusive license to use our ZFP technology for protein pharmaceutical production and Hoffmann–La Roche Ltd and Open Monoclonal Technology, Inc. have non-exclusive rights to the technology in transgenic animal production.