using zinc fingers to control genes

Every cell in our body contains the same genes. Yet, neurons, muscle cells, and skin cells look and work differently. To specialize, our cells turn certain genes on or off when needed. Our cells often regulate gene expression by relying on zinc finger proteins, a class of transcription factors that recognize and bind to specific sequences of DNA code, enabling a cell to differentiate the targeted gene from thousands of others. The family of zinc finger proteins (ZFPs) are among the most common genes in the human genome.

HOW OUR ZFP-TF GENOME REGULATION WORKS

A ROBUST PIPELINE OF GENOMIC MEDICINES

OUR PIPELINE

Sangamo presentations + Publications

Our broad collection of publications, authored by our own scientists, collaborators, and others, contains original research articles and review articles that are relevant to our ZFP technology and its many applications.

 

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