Sangamo uses its deep scientific expertise and proprietary zinc finger technology to create genomic cures for patients suffering from severe diseases for which today’s medicine can only offer symptom management at best.
Explore our pipelineCORE NEUROLOGY PIPELINE | |||||
Indication | Preclinical | Phase 1/2 | Pivotal | Partner | Commentary |
Chronic Neuropathic Pain (Nav 1.7) | Data presented at ASGCT 23 | None |
Nav 1.7 IND-enabling activities continue to advance |
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Prion Disease | Data presented at ASGCT 24 | None |
Prion CTA-enabling activities continue to advance |
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Tauopathies | Data presented at ASGCT 24 |
Genentech
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August 2024: Announced epigenetic regulation and capsid delivery license agreement with Genentech | ||
Undisclosed |
Genentech
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August 2024: Announced epigenetic regulation and capsid delivery license agreement with Genentech | |||
ALS/FTD | Data presented at ASGCT 24 |
Alexion
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None |
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Huntington's Disease |
Takeda
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None |
OTHER PROGRAMS | |||||
Indication | Preclinical | Phase 1/2 | Pivotal | Partner | Commentary |
Hemophilia A (Giroctogene fitelparvovec) | Data presented at ASH 2023 |
Pfizer
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July 2024: Positive topline readout in Phase 3 AFFINE trial. Pfizer plans to discuss data with regulatory authorities in coming months. | ||
Fabry Disease (Isaralgagene civaparvovec) | Data presented at WORLDSymposium 2024 | None |
Continue to amass encouraging clinical data. Potential partnership discussions ongoing. |