Neurology Conference Presentations Hub

Welcome to our Neurology Conference Presentations Hub, a dedicated space with access to the presentations Sangamo delivers at industry leading conferences. Learn about our latest preclinical research and results while gaining insights into our wealth of neurology knowledge.

Viral Engineering for CNS Delivery: Intravenous Delivery
Chronic Neuropathic Pain
Prion
Tauopathies
Amyotrophic Lateral Sclerosis (ALS)
Synucleinopathies
Neurodevelopmental Disorders
Huntington’s Disease
Multiple Sclerosis

Viral Engineering for CNS Delivery: Intravenous Delivery

Corporate Call and Q4 Update

Process and Formulation Development for a Novel Blood-Brain Barrier Penetrant AAV Capsid

Chronic Neuropathic Pain

Publication bioRxiv

Potent and selective repression of SCN9A by engineered zinc finger repressors for the treatment of neuropathic pain
CRL Biotechnology Symposium 2023

Preclinical Development of a Zinc Finger Transcriptional Repressor Targeting the SCN9A Gene as a Novel Therapy for Peripheral Neuropathic Pain
American College of Toxicology 2023

Preclinical Development of a Novel Gene Therapy for the Treatment of Peripheral Neuropathic Pain Through Zinc Finger Repressor- Mediated Repression of the SCN9A Gene
Annual Pain Therapeutics Summit 2023

Zinc finger mediated epigenetic repression of SCN9A gene as a therapeutic approach for painful peripheral neuropathies
ASGCT 2023

Zinc Finger Transcriptional Regulator Mediated Repression of SCN9A Gene as a Therapeutic Approach for Painful Peripheral Neuropathies

Prion

Tauopathies

Science Advances

Persistent repression of tau in the brain using engineered zinc finger protein transcription factors

Amyotrophic Lateral Sclerosis (ALS)

ASGCT 2021

Selective repression of C9ORF72 repeat expansion-containing sense and antisense transcripts for the treatment of ALS

Synucleinopathies

ASGCT 2021

Zinc Finger Protein Transcription Factors Targeting Alpha-synuclein - A Promising Therapeutic Strategy for Parkinson’s Disease

Neurodevelopmental Disorders

Huntington’s Disease

Nature Medicine

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease

Multiple Sclerosis

ESGCT 2023

Myelin Oligodendrocyte Glycoprotein (MOG)-CAR-Tregs – A novel approach to treat multiple sclerosis

Global epigenetic regulation and capsid delivery license agreement with Genentech

Neurology Conference Presentations Hub

Process and Formulation Development for a Novel Blood-Brain Barrier Penetrant AAV Capsid

Potent and selective repression of SCN9A by engineered zinc finger repressors for the treatment of neuropathic pain

Preclinical Development of a Zinc Finger Transcriptional Repressor Targeting the SCN9A Gene as a Novel Therapy for Peripheral Neuropathic Pain

Preclinical Development of a Novel Gene Therapy for the Treatment of Peripheral Neuropathic Pain Through Zinc Finger Repressor- Mediated Repression of the SCN9A Gene

Zinc finger mediated epigenetic repression of SCN9A gene as a therapeutic approach for painful peripheral neuropathies

Zinc Finger Transcriptional Regulator Mediated Repression of SCN9A Gene as a Therapeutic Approach for Painful Peripheral Neuropathies

Neuron-Specific Expression of Zinc-Finger Repressors Mediate Widespread Prion Reduction in the Brain for the Potential Treatment of Prion Disease

Engineered Zinc Finger Transcriptional Regulators Specifically Reduce Prion Expression and Extend Survival in an Aggressive Prion Disease Model

ZF-transcription factors for Prion Disease

Persistent repression of tau in the brain using engineered zinc finger protein transcription factors

Selective repression of C9ORF72 repeat expansion-containing sense and antisense transcripts for the treatment of ALS

Zinc Finger Protein Transcription Factors Targeting Alpha-synuclein - A Promising Therapeutic Strategy for Parkinson’s Disease

Zinc Finger Activators restore normal gene and protein expression in a mouse model of SCN2A haploinsufficiency

Shank3 Gene Activation Mediated by Zinc Finger Activators (ZF-As) as a Therapeutic Approach for Phelan-McDermid Syndrome

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease

Myelin Oligodendrocyte Glycoprotein (MOG)-CAR-Tregs – A novel approach to treat multiple sclerosis